A clinical study involves research using human volunteers (also called participants or subjects) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies.
In a clinical trial, participants receive specific interventions according to the research plan (protocol) created by the sponsor and investigators. These interventions may be medical products, such as drugs or devices; procedures; or changes to participants' behaviour, such as diet.
Clinical trials may compare a new medical approach to a standard one that is already available, to a placebo that contains no active ingredients, or to no intervention. Some clinical trials compare interventions that are already available. When a new product or approach is being studied, it is not usually known whether it will be helpful, harmful, or no different than available alternatives (including no intervention).
The drug or treatment under investigation in the clinical trial may be:
The investigators try to determine the safety and efficacy of the intervention by measuring certain outcomes in the participants. Clinical trials are vital for reliable information about the effects of different treatments, ensuring that treatment options are effective and safe. Before a clinical study can begin, an independent Ethics Committee and if appropriate a Regulatory Authority will evaluate and check that the proposed study is safe, and not likely to cause harm to volunteers. All studies are formally approved prior to any participant enrolling in a trial.
Clinical trials used in drug development are sometimes described by phases. The Heart Lung Centre specialises in delivery clinical trials in early drug development (Phase I, II and III).
The results of controlled trials help to develop a sound evidence base, which doctors and patients can use when making treatment decisions. In offering a reliable evidence base, doctors can be more confident that they are using treatments that have been shown to have beneficial effects and that resources can be allocated to effective therapies.
Every clinical trial has specific requirements for who is able to participate in a clinical research study. We will assess if you are able to participate in our current trials during your registration visit. We always have a number of trials available with different entry criteria.
Your details will be kept on our database and we will consider you for future research. The candidates required for our studies change based on the criteria, and any new studies may bring forth new opportunities for volunteering.
I have registered! What happens now?
Once the registration form has been completed, we will call you shortly to confirm your details and discuss any potential trials you may be suitable for.
How do I find you?
Queen Anne Street Medical Centre is a short walk from Bond Street and Oxford Circus stations. Please follow this map to find us.
How much do the trials pay?
Our trials vary greatly in terms of time spent on the unit and the number of procedures performed. Once we have identified a suitable trial, we can inform you of the potential compensation for your participation.
Are clinical trials safe?
All our trials are reviewed by an independent Research Ethics Committee, who ensure that our trials are as safe as possible.
Am I reimbursed for my travel?
Travel payments are reimbursed on a study specific basis. More details of this will be provided for you once you are allocated to a specific study.
Can I choose which study I take part in?
Once we have gathered all the necessary information, we will inform you about the trials you may be able to participate in. You can then decide if you wish to enrol onto the study.
When are you open and how do I contact you?
The Heart Lung Centre is open Monday to Friday from 8am to 5pm for general enquiries.
You can give us a call on 0800 023 4824 or email us at email@example.com